Ana Lleo

Humanitas University, Italy

I obtained my degree in Medicine from the University of Milan, Italy, in 2000, completed my clinical training and received the Board Certification in Internal Medicine and Hepatology in 2006. In the same year I started my PhD at the University of California-Davis (Davis, CA, USA) in the division of Clinical Immunology and Rheumatology, under the supervision of Prof. M. Eric Gershwin. During my PhD I focused on the pathogenesis of PBC and the biliary specificity, a major unanswered question in PBC.

In June 2017, I assumed the responsibility of the Center for Autoimmune Liver Diseases and the Hepatobiliary Immunopathology Laboratory in Humanitas and in January 2022 I was appointed Full Professor of Internal Medicine and Head of the Residency Program in Internal Medicine in Humanitas University. I currently work as Senior Consultant Hepatologist and lead the Autoimmune Liver Diseases Clinic. I am also PI of a laboratory focused on projects of translational nature in liver tumors and, more broadly, in biliary liver diseases. Our studies dealt mainly with clinical and etiopathogenetic aspects of biliary disorders, with particular attention for cholangiocyte biology and liver innate immune response. Our efforts are aimed at translating knowledge from bench to bedside; our final goal is to identify prognostic predictors and molecular targets, and to facilitate their implementation into the clinical management of patients.